Gabriele Schiaffini

High-fat diet, adipokines and low-grade inflammation are associated with disrupted tendon healing: a systematic review of preclinical studies

Silvia Elli, Gabriele Schiaffini, Marina Macchi, Matteo Spezia, Emanuele Chisari, Nicola Maffulli Background The aetiopathogenesis of tendinopathy is uncertain, but inflammation may play a role in the early phase of tendinopathy and in tendon healing response. We investigated the most up-to-date evidence about the association between obesity, high-fat diet and tendinopathy, focusing on the role …

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Tipologie di studio scientifico: Studio Osservazionale

Quando parliamo di ricerca scientifica, gli studi possono essere di diverse tipologie, che differiscono tra loro per quanto riguarda i protocolli, il design e il tipo di investigazione. La prima, e formalmente più ampia distinzione è tra studi osservazionali e sperimentali.   Studi Osservazionali Studiano fattori d’interesse di una popolazione rispetto ad un’altra.  In questo …

Tipologie di studio scientifico: Studio Osservazionale Leggi altro »

Obesity increases the risk of tendinopathy, tendon tear and rupture, and postoperative complications: a systematic review of clinical studies

Marina Macchi, Matteo Spezia, Silvia Elli, Gabriele Schiaffini, Emanuele Chisari Background Inflammation and mechanical demands play a role in the development of tendon conditions and the dysregulation of tendon healing. In patients with obesity, high levels of pro-inflammatory cytokines and a high mechanical demand promote chronic low-grade inflammation. Although controversial results have been reported, we …

Obesity increases the risk of tendinopathy, tendon tear and rupture, and postoperative complications: a systematic review of clinical studies Leggi altro »

The effect of tobacco smoking during pregnancy and breastfeeding on human milk composition—a systematic review

Marina Macchi, Laura Bambini, Simone Franceschini, Ioana Diana Alexa, Carlo Agostoni Introduction Tobacco smoking is still a widespread habit in pregnant and breastfeeding women. While the role of these risk factors on neonatal outcomes has been deeply studied, their effect on human milk composition is still not completely clear. This study aimed to report the …

The effect of tobacco smoking during pregnancy and breastfeeding on human milk composition—a systematic review Leggi altro »

The impact of preoperative anxiety on patients undergoing brain surgery: a systematic review

Vittorio Oteri, Anna Martinelli, Elisa Crivellaro, Francesca Gigli Introduction Preoperative anxiety is a common reaction exhibited by up to 80% of patients who are scheduled for surgical procedures and characterized by psychological and physical changes which may affect their perioperative period. Our aim is to report the most up-to-date evidence on preoperative anxiety in brain surgery …

The impact of preoperative anxiety on patients undergoing brain surgery: a systematic review Leggi altro »

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